This expert guidance provides a framework to guide practitioners in when to evaluate a nursing home resident for infection when a resident exhibits non-specific signs or symptoms, including: fever, hypothermia, low blood pressure, high blood sugar, and delirium. The authors also discuss symptoms, including behavioral changes, functional decline, falls, and anorexia, which own should not prompt further evaluation for infection but should be considered in full context of the patient’s condition.

Full text:

Press release: Guidance on Non-Specific Symptoms of Infection Aims to Reduce Inappropriate Antibiotic Use in Nursing Homes

Pocket card: Nursing Home Infections: Reliability of Non-Localizing Signs and Symptoms in Evaluating for Infection

Management of healthcare personnel living with hepatitis B, hepatitis C, or human immunodeficiency virus in US healthcare institutions



  • Webinars:
    • New Guidance for OR Anesthesia – Recommendations for Preventing Infections
    • Infection Prevention in Anesthesia Q&A
    • Implementing Changes for Infection Prevention in Anesthesia
  • Pocket Card
  • ASA Statement 


In Development: 

  • Respiratory Infections

Pocket Cards:

Expert Guidance on Contact Precautions for Drug-Resistant Infections


Pocket Card

Tool Kits: 

  • Incident Management
  • Horizontal Strategies
  • Emerging Pathogens
  • Communication, Negotiation, and Implementation

SHEA/CDC Outbreak Response Training Program:

Chinese Translation:

Part I
Part II
Part III
Part IV


Pocket Card Digital and Print Orders: 

Medscape Slide Summary:

In 2003, the Cystic Fibrosis (CF) Foundation published recommendations for infection prevention and control (IP&C) in an effort to reduce the risk of acquisition and transmission of pathogens among people with CF.1 However, both IP&C and CF are dynamic disciplines, and during the past decade new knowledge and new challenges necessitated the development of updated IP&C strategies for this unique population.

Reviewed August 2018.


Reviewed June 2018.

Three family education guides focusing on hand hygiene, respiratory etiquette, and safe handling of blood and body fluids were also created as part of this guideline but are not contained in this document. These guides are tools to educate families about how to help with minimizing the risk of pathogen transmission. These guides can be found at Patient Guides on Healthcare-Associated Infections.

Reviewed November 2018.

The guidelines are intended to provide practitioners with a standardized approach to the rational, safe, and effective use of antimicrobial agents for the prevention of surgical-site infections (SSIs) based on currently available clinical evidence and emerging issues.

Press Release
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Reviewed March 2018.

Creutzfeldt‐Jakob disease (CJD) is a degenerative neurologic disorder of humans. CJD is caused by a proteinaceous infectious agent. Prion diseases elicit no immune response, result in a noninflammatory pathologic process confined to the central nervous system, have an incubation period of years, and usually are fatal within 1 year after diagnosis.


Reviewed 2014.